Does the Renin-Angiotensin System (RAS) Regulate also Intraocular Pressure (IOP)?
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منابع مشابه
Does the Renin-Angiotensin System (RAS) Regulate also Intraocular Pressure (IOP)?
The central role of Renin-Angiotensin System (RAS) in the regulation of blood pressure is widely accepted, and drugs which inhibit the formation of the potent vasoconstrictor angiotensin II (AngII) i.e. ACE inhibitors or drugs which block the Ang receptors of type 1 (AT1R) form the cornerstone in the treatment of hypertension. However, from AngI and AngII also vasodilating and blood pressure lo...
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Unilateral ureteral obstruction (UUO) is a clinical scenario that leads to obstructive nephropathy. UUO alters the expression of many mediators in the ipsilateral kidney. Renin-angiotensin system (RAS) is involved in UUO. Angiotensin II (Ang II) and angiotensin 1-7 (Ang 1-7) as the main arms of RAS influence kidney function which may alter by UUO. Ang II via Ang II receptor subtypes I (AT1R) ...
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For more than a century, the renin–angiotensin system (RAS) has been recognized as an important part of the physiological system that regulates sodium and water homeostasis, renal function, and systemic blood pressure. The RAS consists of an enzyme/substrate cascade generating angiotensin II (Ang II). Initially the RAS was considered an endocrine system. By activating cellular receptors, circul...
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ژورنال
عنوان ژورنال: The Open Conference Proceedings Journal
سال: 2010
ISSN: 2210-2892
DOI: 10.2174/22102892010010100115